منابع مشابه
The ADVANCE study: a groundbreaking trial to evaluate a candidate universal antiretroviral regimen
PURPOSE OF REVIEW Current WHO-recommended first-line therapy in low-income and middle-income countries has been very successful in saving millions of lives but still has toxicity concerns and a low barrier to resistance. RECENT FINDINGS Two candidate antiretrovirals may substantially transform first-line therapy in low-income and middle-income countries, yielding a safer, more robust and chea...
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Laboratory interactions (Quality of Evidence: high; no clinical significance) • Cobicistat (Stribild®, Tybost®), rilpivirine (Edurant®, Complera®) and dolutegravir (Tivicay®) containing regimens will increase serum creatinine by approximately 7-15 μmol/L during the first 4 weeks of treatment initiation due to inhibition of renal creatinine secretion. This does not reflect an actual decrease in ...
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Purpose of study Even with the introduction of once daily antiretroviral (ARV) regimens of low pill burden, long-term adherence remains a challenge, particularly in subgroups, such as patients with drug addiction. We aimed to determine levels of adherence and identify factors associated with suboptimal adherence in treated, HIV-infected patients attending a busy European inner-city HIV outpatie...
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In a cohort of 128 human immunodeficiency virus-infected patients, we found that patients' knowledge of antiretroviral dosing was suboptimal at regimen initiation but improved with time. Poor medication knowledge 8 weeks after regimen initiation was associated with lower adherence and with a lower level of literacy in a multivariate model (P=.03). Because knowledge deficits are common after ant...
متن کاملSteps toward universal coverage.
The health care reform debate of 1993-1994 revealed widespread recog nition that our nation’s health care system has significant problems. These problems did not end with the debate’s end in the 103d Congress. We therefore have no choice but to try again. Our new effort will reflect not only values and policy judgments but also political lessons from our recent experience. In this paper we argu...
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ژورنال
عنوان ژورنال: Current Opinion in HIV and AIDS
سال: 2017
ISSN: 1746-630X
DOI: 10.1097/coh.0000000000000386